Description

LncRNA H19X was silienced in dermal fibroblats of systemic sclerosis patients with antisense oligonuclotides. The hypothesis tested in the present study was that H19X is an important factor in the development of TGFb-driven fibrosis. Results provide important information about the role H19X in fibroblasts in particolar on extracellular matrix production and cell cycle regulation.

Publication Title

Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis.

Sample Metadata Fields

Specimen part, Disease, Disease stage, Treatment