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accession-icon SRP189768
Porcine Jejunum Transcriptome Sequencing
  • organism-icon Sus scrofa
  • sample-icon 25 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

RNA-Seq of jejunum for 30 pigs with divergent feed efficiency phenotypes

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon SRP189144
Porcine Hypothalamus Transcriptome Sequencing
  • organism-icon Sus scrofa
  • sample-icon 28 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

RNASeq of hypothalamus for 30 pigs with divergent feed efficiency phenotypes

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE107497
Genomic analysis for hematopoietic stem and progenitors cells (HSPC) generated in vitro according to ex vivo expansion protocols and their comparison with HSPC obtained fresh
  • organism-icon Homo sapiens
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Expansion for hematopoietic cells from umbilical cord blood is a strategy for use this cell source in clinic transplants, however, it is important to know about the genomic changes that can occur in expanded cells. In order to detect global expression profiles changes in hematopoietic stem and progenitors cells generated in vitro, we analyzed hematopoietics populations obtained by FACS in fresh from umbilical cord blood. HSC (fHSC) was defined as CD34+ CD38- CD71- CD45RA- Lin- and were cocultured with stromal cell line OP-9 plus FL, SCF, IL3, IL6, TPO, GMCSF and G-CSF by 7 days, after time we repurified HSC population by FACS using same immunophenotype (ivHSC). In other hand, fresh erythroid progenitors cells (fEPC) were identified as CD34+CD38+CD71+CD45RA- Lin- and fresh myeloid progenitors cells (fMPC) were identified as CD34+CD38+CD71-CD45RA+Lin-. In vitro progenitors cells (ivEPC and ivMPC) were obtained by culturing fHSC in Stemspan serum-free media plus SCF, TPO, IL6, FL and IL3 by 10 days, after time cells were repurified by FACS using same immunophenotype for fresh progenitors. In vitro generated cells were compared with their corresponding fresh population cells.

Publication Title

Functional Integrity and Gene Expression Profiles of Human Cord Blood-Derived Hematopoietic Stem and Progenitor Cells Generated In Vitro.

Sample Metadata Fields

Specimen part

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accession-icon E-MTAB-2904
Collagen induces maturation of human monocyte-derived dendritic cells by signalling through Osteoclast Associated Receptor
  • organism-icon Homo sapiens
  • sample-icon 96 Downloadable Samples
  • Technology Badge Icon Affymetrix HT HG-U133+ PM Array Plate (hthgu133pluspm)

Description

Human immature dendritic cells derived from monocytes were activated to become mature dendritic cells by exposure to platebound Collagen I or Collagen. The importance of OSCAR-signalling was evaluated by pre-incubating the immature dendritic cells with an inhibitory monoclonal antibody to the OSCAR receptor, or an isotype control. As a positive control, immature dendritic cells were activated by using LPS. The set-up was examined at 4 hours and 20 hours to evaluate early and late effects of OSCAR signalling.

Publication Title

Collagen induces maturation of human monocyte-derived dendritic cells by signalling through Osteoclast Associated Receptor

Sample Metadata Fields

Specimen part, Subject, Compound, Time

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accession-icon DRP004999
The presence of RNA in murine spermatozoa
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2500

Description

The presence of RNA in the spermatozoa collected in HTF medium from cauda epididymis of 12-week-old C57/BL6 male mice.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Cell line

View Samples
accession-icon SRP089840
Transcriptome of hair follicle epidermal stem cells
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 1500

Description

Mouse hair follicles contain distinct epidermal stem cell populations that reside in their own microenvironments. To understand their molecular identities and surrounding microenvironments, each stem cell compartment was isolated from several different eGFP reporter mouse lines by FACS and their transcriptome data was obtained by RNA sequencing.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
accession-icon DRP003275
Gene expression profiling of granule cells and Purkinje cells in zebrafish cerebellum
  • organism-icon Danio rerio
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq1500

Description

An RNA-seq analysis was performed using zebrafish granule cells, Purkinje cells, IO neurons, and glial cells. The transcriptomes were sequenced using Illumina HiSeq with paired-end libraries employing the Quartz-seq method for low amount total RNA.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE15271
Expression data from CXCR4pos (centroblast) and CXCR4neg (centrocyte) Human Germinal Center B cells
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Functional discrimination between normal centroblast and centrocyte obtained from human inflamed tonsils after cell sorting.

Publication Title

CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells.

Sample Metadata Fields

Specimen part

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accession-icon GSE97743
Host transcription profile in nasal epithelium and blood of hospitalized children under two years old with Respiratory Syncitial Virus infection
  • organism-icon Homo sapiens
  • sample-icon 332 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection.

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage

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accession-icon GSE97741
Host transcription profile in nasal epithelium and blood of hospitalized children under two years old with Respiratory Syncitial Virus infection [whole blood]
  • organism-icon Homo sapiens
  • sample-icon 166 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

Analysis of transcriptional profiles in whole blood and nasopharyngeal swaps from children hospitalized with lower respiratory tract infections at their admission and their discharge, and diagnosed with either RSV or rhinovirus infections.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease stage

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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