Effect of IPMS (BatIMS) overexpression on Arabidopsis thaliana.
Expression of a Brassica isopropylmalate synthase gene in Arabidopsis perturbs both glucosinolate and amino acid metabolism.
Age, Specimen part
View SamplesAML patient samples and a few normal blood sample were assayed for H3K27ac ChIP-seq and RNA-seq. We discovered subtypes of AML based on these enhancer landscapes.
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View SamplesLITE-Seq 3'' end capture and sequencing of the C. elegans germline
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Sex, Specimen part, Cell line
View SamplesThis microarray experiment serves to identify the genes in the Arabidopsis genome that are regulated by carbon and light signaling interactions in 7 day dark grown seedlings. The expression profile of wild-type will be compared to the cli186 mutant, a mutant defective in carbon and light signaling. Plants of both the wild-type and cli186 genotypes are treated with the following light (L) and carbon (C) treatments: -C-L, +C-L, +C+L, -C+L. Comparison of the expression profiles under all treatments will help to identify genes that are misregulated in carbon and/or light treatments in the cli186 mutant.
An integrated genetic, genomic and systems approach defines gene networks regulated by the interaction of light and carbon signaling pathways in Arabidopsis.
Age
View SamplesHeart tissue was enriched from 48hpf zebrafish larvae from different experimental conditions. Approximately 200 hearts were collected for each sample. The goals of the study were to profile transcriptional outputs in the cardiac tissue which affects heart development between two different experimental conditions.
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View SamplesThe goal of the experiment was to simulate the effect of size-selective harvesting and captive rearing on gene expression in a controlled environment using zebrafish as a model species.
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View SamplesStudy Goals: To understand the impact of macrophage retention of exosomes on macrophage gene expression and function. Additionally, we also wanted to understand the effect of TLR3 stimulation of HEY cells on exosome mediated macrophage functionsRelevance: Exosomes have a multitude of effects in immunomodulation and cancer cells secrete exosomes that alter the fate of cancer progression. In this study we seek to: 1) understand the effect of TLR stimulation on local cells producing exosomes2) understand the impact of cancer secreted exosomes on cancer progression.
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Sex, Age, Specimen part, Disease, Cell line, Treatment
View SamplesStudy goals:To understand the impact of sustained lymph node retention of exosomes on whole lymph node gene expression and function.Relevance: Exosomes have a multitude of effects in immunomodulation and cancer cells secrete exosomes that alter the fate of cancer progression. In this study we seek to: 1) understand the effect of TLR stimulation on local cells producing exosomes 2) understand the impact of cancer secreted exosomes on cancer progression.
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Sex, Age, Specimen part, Disease, Cell line, Treatment
View SamplesTotal RNA-Seq from starved Drosophila melanogaster mutant strains fkbp14, trsn, and iso31 control strain.
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Sex, Age, Specimen part
View SamplesMOTHER-OF-FT-AND-TFL1 is a key repressor of seed germination under far-red light in Arabidopsis thaliana
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Specimen part, Treatment
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