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accession-icon E-MEXP-380
Transcription profiling of human NK cells sorted into CD56dim and CD56bright NK cell subpopulations
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Description

Human NK cells were sorted into CD56dim and CD56bright NK cell subpopulations. In order to define characteristics of both populations gene profiling was performed using Affymetrix arrays U133a and U133B.

Publication Title

Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells.

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-384
Transcription profiling of human precursor-B-cell differentiation
  • organism-icon Homo sapiens
  • sample-icon 25 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Description

We purified five subsets representing the main stages of human precursor-B-cell differentiation and CD34+lin- cord blood cells. The immunoglobulin (Ig) gene rearrangement status was determined using TaqMan quantitative PCR and GeneScan analysis. To gain more insight in the networks of genes that initiate and/or regulate the different types of Ig gene rearrangements, we analyzed their gene expression profiles by correlating the initiation of Ig gene rearrangements with specific upregulation of transcription factors. In addition to previously described transcription factors, we identified 16 candidate genes involved in initiation and/or regulation of Ig gene rearrangements.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-337
Transcription profiling by array of human T-cell differentiation
  • organism-icon Homo sapiens
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T-cell developmental stages, including CD34+ lin- cord blood cells as a reference. The same stages were used for gene expression profiling using DNA microarrays.

Publication Title

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

Sample Metadata Fields

Specimen part

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accession-icon SRP157911
Influence of pH on Gene Expression Profiles of Bone-marrow-derived Macrophages
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Investigation of pH induced gene expression changes in bone-marrow-derived macrophages

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Treatment

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accession-icon SRP157897
Expression Analysis of Tumor-associated Macrophages in B16 Melanoma Tumor Model
  • organism-icon Mus musculus
  • sample-icon 7 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Inverstigation of differential gene expresseion in tumor-associated macrophages of WT-and Icer- knockout mice

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

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accession-icon GSE9254
Normal human colorectal mucosa, cecum, ascending, transverse, sigmoid and rectum
  • organism-icon Homo sapiens
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Normal human colorectal mucosa was sampled at points along the colon.

Publication Title

Map of differential transcript expression in the normal human large intestine.

Sample Metadata Fields

Specimen part

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accession-icon SRP056985
Homo sapiens Raw sequence reads
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

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Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP097584
Mus musculus Raw sequence reads
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

T cell lymphoma

Publication Title

PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP068247
Gallus gallus Transcriptome or Gene expression
  • organism-icon Gallus gallus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

To understand the molecular mechanisms underlying AS progression, we assessedblood collected from disease and normal groups and obtained pulmonary arteries fromAS and normal broilers for pathological observation and RNA-seq analysis.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon GSE69421
Genetic background of immune complications
  • organism-icon Homo sapiens
  • sample-icon 51 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

Differencies between groups between pre and post haematopoietic stem cell transplantation children

Publication Title

Genetic Background of Immune Complications after Allogeneic Hematopoietic Stem Cell Transplantation in Children.

Sample Metadata Fields

Specimen part, Disease stage

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...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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