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accession-icon E-MEXP-432
Transcription profiling of inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system in continuous light
  • organism-icon Arabidopsis thaliana
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system. Plants harboring 35S::AlcR/AlcA::GOI (GUS control, LEAFY, SHOOTMERSTEMLESS, WUSCHEL)constructs were grown in continous light for 12 days and induced with 1% Ethanol. After 12h of EtOH treatment, seedlings were dissected and RNA was processed from the shoot apex and young leaves. Affymetrix Ath1 arrays were hybridized in duplicates from each experiment.

Publication Title

WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators.

Sample Metadata Fields

Age, Specimen part, Subject, Compound

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accession-icon E-MEXP-1468
Transcription profiling of Arabidospsis etiolated seedlings Col-0 wild type compared to det3 mutants under various growth conditions
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Arabidopsis etiolated seedlings (4d old) Col-0 wild type compared to det3 mutants under various growth conditions

Publication Title

Reduced V-ATPase activity in the trans-Golgi network causes oxylipin-dependent hypocotyl growth Inhibition in Arabidopsis.

Sample Metadata Fields

Age

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accession-icon E-MEXP-1100
Transcription profiling of Arabidopsis seedlings with disturbed function of CDKB2;1 and CDKB2;2 by either overexpression or knock-down
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Comparison of Arabidopsis seedlings with disturbed function of CDKB2;1 and CDKB2;2 by either overexpression or knock-down

Publication Title

Requirement of B2-type cyclin-dependent kinases for meristem integrity in Arabidopsis thaliana.

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-879
Transcription profiling of Drosophila embryos at stages 11 and 12 to identify genes downstream of Hox
  • organism-icon Drosophila melanogaster
  • sample-icon 48 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Identification of Hox gene downstream genes at embryonic stages 11 and 12<br></br><br></br>Functional diversification of body parts is dependent on the formation of specialized structures along the various body axes. In animals, region-specific morphogenesis along the anterior-posterior axis is controlled by a group of conserved transcription factors encoded by the Hox genes. Although it has long been assumed that Hox proteins carry out their function by regulating distinct sets of downstream genes, only a small number of such genes have been found, with very few having direct roles in controlling cellular behavior. We have quantitatively identified hundreds of Hox downstream genes in Drosophila by microarray analysis, and validated many of them by in situ hybridizations on loss- and gain-of-function mutants. One important finding is that Hox proteins, despite their similar DNA binding properties in vitro, have highly specific effects on the transcriptome in vivo, as expression of many downstream genes responds primarily to a single Hox protein. In addition, a large fraction of downstream genes encodes realizator functions, which directly affect morphogenetic processes, such as orientation and rate of cell divisions, cell-cell adhesion and communication, cell shape and migration, or cell death. Focusing on these realizators, we provide a framework for the morphogenesis of the maxillary segment. Since the genomic organization of Hox genes and the interaction of Hox proteins with specific cofactors are conserved in vertebrates and invertebrates, and similar classes of downstream genes are regulated by Hox proteins across the metazoan phylogeny, our findings represent a first step towards a mechanistic understanding of morphological diversification within a species as well as between species.

Publication Title

Comparative analysis of Hox downstream genes in Drosophila.

Sample Metadata Fields

Age, Time

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accession-icon E-MEXP-2270
Transcription profiling by array of Arabidopsis mutant for arr7 and/or arr15 after treatment with cytokinin, auxin or both
  • organism-icon Arabidopsis thaliana
  • sample-icon 32 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Above ground tissue of 10 day old Arabidopsis seedlings of Col wild-type, 35S-ARR7, arr7, 35S-ARR15 was treated with Cytokinin (benzyladenine), Auxin (indole-3-acetic acid) or both.

Publication Title

Hormonal control of the shoot stem-cell niche.

Sample Metadata Fields

Age, Specimen part, Treatment

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accession-icon E-MEXP-1592
Transcription profiling of apex and flowers of Arabidopsis Landsberg errecta wild type and slm mutant plants
  • organism-icon Arabidopsis thaliana
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

comparison of Landsberg errecta wild-type with slm mutants in apex and flowers

Publication Title

DETORQUEO, QUIRKY, and ZERZAUST Represent Novel Components Involved in Organ Development Mediated by the Receptor-like Kinase STRUBBELIG in Arabidopsis thaliana

Sample Metadata Fields

Age, Specimen part

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accession-icon E-MEXP-2041
Transcription profiling of Arabidopsis apices from control and smz-D flc-3 knock-out plants after photoperiod induction
  • organism-icon Arabidopsis thaliana
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Response of control (flc-3) and dominant late flowering mutant (smz-D flc-3) to inductive photoperiod (tissue: apices)

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Time

View Samples
accession-icon E-MEXP-1799
Transcription profiling of Arabidopsis Bur-0 and Pf-0 ecotypes grown at 23 or 27 degrees C to compare expression profiles between greenworms and wildtype looking plants
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Comparison of expression profiles between greenworms and wildtype looking plants

Publication Title

A triplet expansion associated genetic defect in Arabidopsis thaliana

Sample Metadata Fields

Age, Specimen part, Disease, Disease stage, Subject

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accession-icon E-MEXP-2040
Transcription profiling of Arabidopsis leaves from control and smz-D flc-3 knock-out plants after photoperiod induction
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Response of Arabidopsis control (flc-3) and a dominant repressor of flowering (smz-D flc-3) to inductive photoperiod

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Time

View Samples
accession-icon GSE60242
Expression data from early Arabidopsis thaliana embryo
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

After zygote division, the resulting daughter cells progressively give rise to two very different tissue types. With the use of microarrays, global nuclear expression profiles were generated.

Publication Title

Cell type-specific transcriptome analysis in the early Arabidopsis thaliana embryo.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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