Description

Using PAXgene tubes, peripheral blood samples were collected from seven patients >18 years with documented pdm(H1N1) influenza, bilateral chest infiltrates, and in need of ventilation support. Significant co-morbidity was exclusion criterion. Expression profiles were compared with 7 age matched controls. Using a false discovery rate < 5% and an absolute fold change > 2, 370 genes were differentially expressed in case and controls.

Publication Title

Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza.

Sample Metadata Fields

Sex, Age, Specimen part, Subject