SRP185891Effect of Rgnef knockout in an aggressive ovarian cancer cell line
Mus musculus
6 Downloadable Samples
Illumina HiSeq 4000Submitter Supplied Information
Description
CRISPR/Cas9-mediated Rgnef knockout was performed in the aggressive ID8-IPs (alternaate name is KMF cells). Gene expression profiles of Rgnef-/- or Rgnef-/- cells re-expressing GFP-Rgnef were generated. Differential downregulation of antioxidant genes was observed in Rgnef-/- cells. Results provide insight into the role of Rgnef in promoting ovarian tumor progression. Overall design: mRNA profiles of ID8-KMF Rgnef-/- or Rgnef-/- cell re-expressing GFP-Rgnef were generated in triplicate using an Illumina HiSeq 4000.
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6
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No associated institution
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ID8IPGR2
derived from id8 cells passaged in-vivo
c57bl6/j
id8-kmf rgnef-/- re-expressing gfp-rgnef
NA
ID8IPGR3
derived from id8 cells passaged in-vivo
c57bl6/j
id8-kmf rgnef-/- re-expressing gfp-rgnef
NA
ID8IPGR1
derived from id8 cells passaged in-vivo
c57bl6/j
id8-kmf rgnef-/- re-expressing gfp-rgnef
NA
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