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Accession IconGSE40491

Expression data from post natal mouse aortic heart valves treated with all-trans retinoic acid or a retinoic acid receptor antagonist (LE540) relative to DMSO treated controls

Organism Icon Mus musculus
Sample Icon 9 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

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Description
Our lab has previously shown that treatment of murine heart valve explants with ATRA promotes calcification in vitro. In order to fully explore gene expression changes in the valve in response to ATRA or LE540, a high throughput microarray was performed.
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DMSO treated aortic heart valve at post natal day 1, biological replicate 3
aortic valve
LE540 treated aortic heart valve at post natal day 1, biological replicate 3
aortic valve
ATRA treated aortic heart valve at post natal day 1, biological replicate 1
aortic valve
DMSO treated aortic heart valve at post natal day 1, biological replicate 1
aortic valve
LE540 treated aortic heart valve at post natal day 1, biological replicate 2
aortic valve
ATRA treated aortic heart valve at post natal day 1, biological replicate 2
aortic valve
ATRA treated aortic heart valve at post natal day 1, biological replicate 3
aortic valve
DMSO treated aortic heart valve at post natal day 1, biological replicate 2
aortic valve
LE540 treated aortic heart valve at post natal day 1, biological replicate 1
aortic valve
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