miR-34a targets PDGFRA in proneural malignant glioma

GSE34242

Homo sapiens

6 Downloadable Samples

Illumina HumanHT-12 V3.0 expression beadchip

Submitter Supplied Information

Description

To identify potential targets of miR-34a, we performed transcriptional profiling on proneural TS543 GBM cells, focusing on mRNAs whose levels decreased in response to miR-34a transfection as compared to control oligonucleotide.

PubMed ID

22479456

Publication Title

miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis.

Total Samples

Submitter’s Institution

Memorial Sloan-Kettering Cancer Center

Authors

Silber J, Jacobsen A, Ozawa T, Harinath G, Pedraza A, Sander C, Holland EC, Huse JT

Source Repository

Gene Expression Omnibus (GEO)

GSM842059

TS543_72h_miR34a_rep2

ts543 proneural gbm

72h post transfection with hsa-mir-34a

GSM842062

TS543_72h_Control_rep2

ts543 proneural gbm

72h post transfection with control oligonucleotide

GSM842060

TS543_72h_miR34a_rep3

ts543 proneural gbm

72h post transfection with hsa-mir-34a

GSM842063

TS543_72h_Control_rep3

ts543 proneural gbm

72h post transfection with control oligonucleotide

GSM842058

TS543_72h_miR34a_rep1

ts543 proneural gbm

72h post transfection with hsa-mir-34a

GSM842061

TS543_72h_Control_rep1

ts543 proneural gbm

72h post transfection with control oligonucleotide