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Accession IconGSE12230

Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430B)

Organism Icon Mus musculus
Sample Icon 8 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Expression 430B Array (moe430b), Affymetrix Mouse Expression 430A Array (moe430a)

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Gene expression profiling was performed on CNS tissue from neonatal mice carrying the T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15. Our analysis revealed the presence of two novel paternally expressed intergenic transcripts at the PWS/AS locus. The transcripts were termed Pec2 and Pec3 for paternally expressed in the CNS.Our analysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS.
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neonatal cortex,T9H/+ patdup proximal Chr 7, matdup proximal Chr 15, 430B
mouse brain from 13.5 dpc embryo, T9H/+ matdup proximal Chr 7, patdup proximal Chr 15, 430B
mouse brain from 15.5 dpc embryo, T9H/+ patdup proximal Chr 7, matdup proximal Chr 15, 430B
mouse brain from 13.5 dpc embryo, T9H/+ patdup proximal Chr 7, matdup proximal Chr 15, 430B
mouse brain from 15.5 dpc embryo, T9H/+ matdup proximal Chr 7, patdup proximal Chr 15, 430B
neonatal cerebellum, T9H/+ matdup proximal Chr 7, patdup proximal Chr 15, 430B
neonatal cortex, T9H/+ matdup proximal Chr 7, patdup proximal Chr 15, 430B
neonatal cerebellum, T9H/+ patdup proximal Chr 7, matdup proximal Chr 15, 430B
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